生殖细胞增殖调控：以果蝇bam基因为切入点的研究
基本信息
结项摘要
细胞增殖调控是器官大小调节和肿瘤发生研究中的核心问题。在果蝇的精子发生过程中，生殖细胞进行精确的四次有丝分裂以扩增其数量。因此这是一个在生物体内研究细胞增殖调控的理想系统。前人发现bam和bgcn的突变cell-autonomously导致spermatogonial cells过度增殖，但是其分子机制至今不明。我们发现bam+/-杂合子果蝇睾丸中有明显的生殖细胞过度增殖表型。更重要的是，这一表型
项目摘要
项目成果
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数据更新时间：2023-05-31
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