DeltaEF1在成骨细胞分化过程中的功能研究
基本信息
结项摘要
δEF1是一个普遍存在的转录抑制因子，对维系骨骼系统正常的发生、发育以及成骨细胞功能具有不容替代的作用，但具体分子机制机制至今不详。本项目拟在前期工作基础上，深入探讨δEF1在成骨细胞增殖与分化过程中所发挥的作用，明确其调控成骨细胞分化的功能定位以及相关的分子机理、调控方式；探讨δEF1影响成骨细胞分化的信号转导途径，明确其在BMP/Smad信号途径中的呈递关系及与其他信号途径的交互作用。.δEF
项目摘要
项目成果
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数据更新时间：2023-05-31
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