靶向基因治疗膀胱癌的实验研究
基本信息
结项摘要
应用人和小鼠Uroplakin-Ⅱ启动子（已证实在人具有膀胱特异启动活性），检测各部分功能以及该启动子对人类细胞的启动活性和组织特异性，将该启动子与肿瘤坏因子基因构建成穿梭载体，利用腺病毒，在体外和动物模型中进行膀胱肿瘤基因治疗的实验研究，为今后应用该启动子地行膀胱癌的治疗、预防奠定基础。
项目摘要
项目成果
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数据更新时间：2023-05-31
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