This project explored the possibilities to synthesize natural alkaloids from enantiopure b-amino acid derivatives. Fourteen alkaloids have been synthesized and three of them were synthesized first. Eight papers were published in international journals.
以光学纯的b-氨基酸衍生物为手性源,开展对于一些具有抗炎,抗肿瘤活性的生物碱的全合成研究。在合成过程中将发展一些不对称合成吡咯烷,吡啶烷等含氮杂环化合物的方法。这一研究,不仅为合成这些天然产物及其衍生物提供一些简便的途径,而且也会丰富氨基峄А?................
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数据更新时间:2023-05-31
DNAgenie: accurate prediction of DNA-type-specific binding residues in protein sequences
黄曲霉毒素B1检测与脱毒方法最新研究进展
Quasispecies characteristic in "a" determinant region is a potential predictor for the risk of immunoprophylaxis failure of mother-to-child-transmission of sub-genotype C2 hepatitis B virus: a prospective nested case-control study.
Interferon-based treatment is superior to nucleos(t)ide analog in reducing HBV-related hepatocellular carcinoma for chronic hepatitis B patients at high risk
Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling
以京尼平为原料的一些萜类天然产物的合成研究
含氟亚胺砌块重排反应和含氟-b-氨基酸衍生物的合成研究
基于炔丙醇为原料的若干天然物和药物的合成
以磷酸酰胺Phaseolotoxin为模型的微生物天然产物氮磷键生物合成研究