ω-3脂肪酸可调控的TNFα表达载体的构建及其抗癌效应
基本信息
结项摘要
利用ω-3多不饱和脂肪酸（ω-3 PUFA ）通过核受体PPAR介导含PPRE增强子的靶基因表达的特点，构建带PPRE的TNFα表达载体，使TNFα在靶细胞中表达受ω-3PUFA诱导；应用细胞嘌吐闶笠浦擦瞿Ｐ停芯喀?3PUFA及其诱导外源性TNFα基因产物在体内、体外联合抗肿瘤作用及其分子机制，探索增强ω-3 PUFA抗癌作用的有效措施，为ω-3 PUFA在肿瘤治疗中的应用开辟新途径。
项目摘要
项目成果
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数据更新时间：2023-05-31
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