甲基汞对脑神经元PKC激活转位及其介导信号通路的影响
基本信息
结项摘要
建立大鼠甲.基汞所致不.同发育阶段.脑损伤模型，取其靶损伤部.位.脑组织，分离神经元崛∩窬?、核组分中.PKC.，测定其亚类分布及活性，并对其介导MAPK、JNK通路中MEK、JNK.活性进行分析，同步探讨甲基汞.对神经元c-fos、.c-jun表达及转录.因子AP-1、NF-kB与序列特异.DNA结性的影响.。揭示甲基.汞.所.致.脑.发.育.损.伤.的.分.子.基.础.，.具.有.重
项目摘要
项目成果
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数据更新时间：2023-05-31
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