人类GJB2相互作用蛋白质与遗传性耳聋关系的初步研究
基本信息
结项摘要
本研究应用酵母双杂交技术，寻找与鉴定人类GJB2相互作用蛋白质，确定其在内耳组织亚细胞的表达及定位情况。研究野生型和突变型GJB2与互作蛋白在内耳细胞相互作用的差异，明确GJB2与互作蛋白相互作用的功能域。研究成果将有助于了解GJB2在听觉生理活动中的作用机理，并为GJB2基因突变所致的遗传性聋进一步开展基因治疗和药物治疗的研究奠定基础。
项目摘要
项目成果
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数据更新时间：2023-05-31
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