基于生物光子相干理论的中医“证候”的定量化探索

The quantification of syndrome in the Traditional Chinese Medicine (TCM) has been the core proposition of modernization of the TCM, and is also the hot and difficult problem of scientific research. Based on the coherence theory of biophoton, we proposed the hypothesis that syndrome is the quantum interference superposition state of the electromagnetic radiation field within human body. And based on the coherence theory, we also derive the mathematical model of syndrome in the TCM, i.e. Sy=ν/ln(6I+1).The project intends to research Kidney Yin Deficiency syndrome and Kidney Yang Deficiency sydrome,use the biophoton analysis system on the basis of preliminary studies, by detecting biophoton intensity of the related acupoints under a certain frequency, according to the theoretical mathematical model of syndrome, and coupled with clinical practice , explore the relationship between biophoton intensity of related acupoints and Kidney Yin Deficiency syndrome and Kidney Yang Deficiency sydrome.Thus reveal the discipline between biophoton intensity of specific body parts ( meridians or acupuncture points ) and the syndrome, and provide theoretical and experimental basis for the quantification of syndrome. And then verify the correctness of the syndrome hypothesis and mathematical model of syndrome we have proposed. Based on the viewpoint of integrity, time and space characteristic of syndrome,we intend to establish a new stable technical method for determining and quantifying the syndrome in the TCM,and search for new indicators for the characterization of the body's overall physiological state according to the biophoton coherent theory, and provide a new technical and research method for the research of modernization of the TCM.

中医证候的客观定量化一直是中医现代化研究的核心命题，也是研究的热点和难点问题。本课题组曾基于生物光子相干性理论，提出证候是机体电磁辐射场量子相干叠加态的假说，并在此理论上推导出中医证候的数理模型，即Sy=ν/ln（6I+1）。本项目在前期研究的基础上拟以肾阳虚证、肾阴虚证为研究对象，利用生物光子分析系统，通过检测一定频率下相关穴位的生物光子强度，分析根据理论推算的数理模型，并结合临床实践，探索相关经络或穴位处的生物光子强度与肾阳虚证、肾阴虚证的相关性，进而揭示证候与机体特定部位（经络或穴位）生物光子辐射强度的变化规律，为证候的定量化提供理论和实验依据；同时验证我们提出的证候量子叠加态假说及数理模型的正确性。本课题基于证候整体性、时空性的观点，建立一种全新的稳定的测定量化证候的技术方法，从生物光子相干性理论的角度寻找可表征机体整体生理状态的指标，为中医现代化研究提供了新的技术手段和研究途径。

中医证候的本质研究一直是中医基础理论现代化研究的热点和难点，对于其物质基础一直众说纷纭，未有定论。本课题组基于生物光子相干性理论，并结合中医基础理论，经过理论推算，提出中医证候量子叠加态假说。基于此假说，我们试图利用生物光子技术和方法通过测量人体手指末端穴位处的自发光子辐射来验证提出的假说。本项目对现有的人体自发生物光子辐射探测系统的性能和最佳实验条件进行了测试和优化，包括实验暗室密闭性、实验环境温度、光电倍增管（PMT）高压、PMT制冷温度，暗适应时间等对探测系统灵敏度的影响，获得了仪器的最佳测试性能和条件；通过对347名不同年龄段、不同性别的健康人的手指指尖末端穴位的自发光子辐射的测量和分析，获得了健康人生物光子辐射规律及其与机体生命状态之间关系的参数及表征指标；通过对健康人、心气虚证、肺气虚证、痰热壅肺证患者之间十指指尖末端穴位的自发生物光子辐射数据的测试分析，明确了气虚证、肺气虚证、痰热壅肺证患者十指指尖末端穴位生物光子辐射与对应证候的相关性，获得了不同证候与机体特定部位生物发光强度的变化规律；通过比较健康人、心气虚证、肺气虚证、痰热壅肺证患者之间十指指尖末端穴位的生物光子辐射的变化规律，初步验证了我们提出的证本质是电磁辐射形成的量子叠加态的假说。基于以上研究结果，初步建立了一种可定量研究中医证的生物光子检测体系和方法，为中医的现代化研究提供了一种新的技术手段和研究途径。