手性Cu纳米团簇的合成及其手性表面的构筑和不对称催化研究

Atomically precise metal nanoclusters draw numerous attentions in recent years, not only for its novel properties, but also for it could act as an ideal system bridging the molecules and nanomaterials. In depth study the metal nanoclusters could benefit understanding the nanomaterials and catalysis essentially on molecular levels, and it’s also much valuable to develop the further application itself. .In this project, we propose to explore the synthesis of chiral Cu nanoclusters and construct the chiral surfaces, establish a general method of stably producing functional Cu nanoclusters. Further to study the asymmetric catalysis with the generated chiral nanoclusters. According to the in-situ characterization and isolation of the key intermediate, investigate the catalytic mechanism and establish the relative model. Based on the work, continue to invest their potential application, such as catalytically producing chiral alcohols. .All these studies would provide a new avenue for the metal nanoclusters’ development and support the design of new nanomaterials and catalysis study.

有机配体修饰的金属纳米团簇兼具分子和纳米材料特征，不仅自身即为一类优异的材料，还可作为连接分子与纳米材料的桥梁，通过精确结构解析，帮助纳米材料在分子水平上进行理解。鉴于此，本项目选择相对廉价的Cu作为金属源，拟进行手性Cu纳米团簇的设计合成，研究其构筑的手性表面和选择性催化性能。通过对合成过程的规律总结和中间体的表征、合成条件与团簇结构的关系分析，探讨手性金属团簇的形成机理，建立手性Cu纳米团簇的合成方法体系。通过原位表征、时间跟踪，结合理论计算等对相关机理进行探讨，增强对纳米团簇材料在催化应用中的相关认识，建立相关催化模型。通过手性Cu纳米团簇的合成及不对称催化研究，促进纳米团簇材料的发展，为开发新型功能性团簇、纳米材料及其催化应用提供指导。

有机配体修饰的金属纳米团簇兼具分子和纳米材料特征，不仅自身即为一类优异的材料，还可作为连接分子与纳米材料的桥梁，通过精确结构解析，帮助纳米材料在分子水平上进行理解、设计并改进。本项目开展了手性Cu纳米团簇的设计合成，通过配体的调控和实验条件的摸索，最终得到了系列铜氢纳米团簇，实现了在常规条件下合成铜纳米团簇；结合单晶结构解析、质谱、核磁共振谱等方法，形成了精确解析纳米团簇组成与结构的系统方法；通过配体的空间排列、手性配体的修饰等，实现了纳米团簇的手性构筑；探索了铜纳米团簇的催化应用，通过原位表征、时间跟踪等，结合理论计算对相关催化机理进行了探讨，建立了相关催化模型。项目完成了手性Cu纳米团簇的合成及催化研究，为促进纳米团簇材料的发展、开发新型功能性团簇、纳米材料及其催化应用提供理论基础。