抗炎中西药调控巨噬细胞TLR4/COX2信息转导途径之机制
基本信息
结项摘要
基于Toll样受体为新发现的细胞模式识别受体，与炎症发生关系密切，其表达状况真接影响COX2的表达，而不同抗炎药物对COX2调控存在明显差异等，本课题拟对抗炎中西药影响巨噬细胞COX2基因表达与TLR4通路的关系进行研究，旨在阐明抗炎中西药的药理作用机制，并找出抗炎中西药物对TOll/COX2信息转导途影响差异，以期为抗炎药物的应用提供线索。
项目摘要
项目成果
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数据更新时间：2023-05-31
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