组织器官区域免疫特性与疾病

The project aims to study on major basic immunology (regional immune) and major needs of the country (major disease), and its purpose is to solve the problems and the bottleneck about population and health. Through the implementation of this project, it may have a new interpretation of regional immunity characteristics of one or some tissues and organs, and give new unknown functions that humans is not yet known. We may also find new important immune cell subsets, explore functional molecules or immune new targets for intervention, and elucidate the fine immunology mechanisms of diseases in the main tissues and organs. The project will lay the foundation or provide the feasible way for the prevention and treatment of these diseases. Of important, we sought to attract and nurture an international advanced level of research teams to carry out the research of regional immunity and diseases through the relative stability and higher intensity of support. The blueprint is to dramatically improve the overall level of immunologic research in China. This project used to support the survey and academic exchanges for the committee of experts of this Major Research Program.

本项目的战略目标是将免疫学的重大基础研究（区域免疫特性）与国家的重大需求（重大疾病）结合起来，其宗旨是解决我们目前面临的人口与健康的难题和瓶颈。通过该重大研究计划的实施，有可能对某个或某些组织器官区域免疫特性进行新的解释，赋予人类尚未认识的新功能；有可能发现新的特定功能的重要免疫细胞或亚群，发掘新的功能分子或免疫干预靶点，并阐明主要组织器官所发生的各类疾病的精细免疫学机制，为从根本上防治这些疾病奠定基础或研制出可行的治疗途径。通过相对稳定和较高强度的支持，吸引和培育一支具有国际先进水平的研究队伍，实现我国在该研究领域的整体研究水平跨越式发展。该项申请经费主要用于专家组调研考察、组织评审、年度交流和国际合作经费以及其他所需经费。