人体呼吸功能活动的无创实时动态监测及传感技术研究

A new idea which monitoring respiratory function activity of human body by means of direct detection of exhalant gases O2 and CO2 has been presented. Based on the transient electrochemistry principle and by combining computer-controlled fast modulated potential technique with microelectrode method, the all-new "pulse potential modulated electrochemical gas sensor" was established for rapid, simultaneous determination of O2 and CO2 at ambient temperature. In this approach, the total time required for the measurement is in the order of a few decamilliseconds. The detection range of O2 is unlimited. The detection range of CO2 is approximately 0 ~ 10 Kpa and the sensitivity of detection increased at lower CO2 concentrations. This novel biomedical sensor techniques integrated with acquisition, treatment and display of signals could be used for the on-invasive, real-time and dynamic monitoring of respiratory function activity for human body.

通过化学与生物、医学、信息学科的交叉渗透，电化学与计算机、硅微机械加工等多种技术方法的融合与优化，研制出以硅为衬底的集人体呼出气体（氧和二氧化碳）信号提取、检测与结果显示等功能于一体的生物医学传感技术和微型传感器系统，实现对人体呼吸功能活动的无创、实时、动态监测。这对于呼吸生理、病理学的基础研究和临床应用都有重要意义。