黑质神经元对代谢负荷的应答与离子通道的作用
基本信息
结项摘要
黑质（Substantia Nigra，SN）是大脑基底节系统的重要部位，其致密带SNc是帕金森病的病灶核团，其网状部SNr是参与全身惊厥控制的关键核团，此部位的神经元活动敏感于细胞内代谢水平，并且在SNc和SNr神经元的受代谢水平调控的离子转运蛋白的表达谱不同。本课题将在脑组织切片、活细胞和单一离子通道水平，运用膜片钳电生理技术、细胞内荧光技术等，从SN神经元膜电位对代谢负荷（metabolic
项目摘要
项目成果
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数据更新时间：2023-05-31
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