听觉下丘频率选择和方位选择相干性神经机制的模型研究

Based on our previous experimental results on coherence between the frequency selectivity and direction selectivity of auditory neurons in frog inferior colliculus, and considering the latest progresses in morphology, physiology, biophysics and behavior studies, we establish a mathematical model about information processing in auditory neurons in frog inferior colliculus using binaural clue. The results from our modeling and simulation suggested that the binaural inhibition played an essential role in the coherence between the frequency selectivity and direction selectivity in inferior colliculus. And pre-synaptic inhibition may play an important role in such binaural inhibition. This model is not only helpful for understanding the neural mechanism of the coherence between the frequency selectivity and direction selectivity, but also provides some new idea for separating acoustical signals from different sources for engineering practice.

利用我们获得的青蛙下丘听觉神经元频率选择和方向选择间相关性的实验结果，结合我们自己和国际上同行在行为学，形态学，生理学，生物物理学研究方面获得的最新进展，建立关于青蛙下丘听觉神经元利用双耳线索进行信息处理的数学模型，探讨听觉脑汉中神经核团的连接方式，为进一步的生理学研究提供借鉴并为声音信号的分离开拓应用前景。