在高等生物和人的基因组中非编码区占到基因组序列的大部分,从生物进化的观点来看,非编码区序列必定具有重要的生物功能。随着大规模转录组研究的深入,大量的实验数据也显示出基因组非编码区不但参与转录调控还能转录出数目众多的非编码RNA基因。但是囿于传统生物学概念这些非编码RNA基因而在功能研究中常被忽略。不断发现的非编码RNA基因同编码基因一样,在肿瘤中的表达水平有很大的差异,在功能上可以促进或抑制细胞增
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数据更新时间:2023-05-31
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