高强度纤维素树脂键联DNA制备新型免疫吸附剂的研究
基本信息
结项摘要
球形纤维素共价键联DNA，制备红斑狼疮免疫吸附剂。研制的球形纤维素在机械强度、化学稳定性等方面优于商品化球脂糖凝胶树脂，更重要的是适合全血灌流，降低治疗费用，便于免疫吸附疗法的普及应用。采用三种方法活化载体固定化DNA，制备的吸附剂均具有理想的吸附性能，尤其是丁二醇二甘油方法，其手臂作用大大提高了吸附性能。制备方法和技术已成熟，能够为动物和临床实验生产吸附装置。已在国外期刊上发表论文一篇，另一篇已接收。国内期刊一篇，另有一篇已投稿。申请中国发明专利一项。已在5次国际会议、一次国内会议上报告本项目成果，达到了国际先进水平。该专利已译成德文，正在申请德国专利。
项目摘要
项目成果
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数据更新时间：2023-05-31
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