催组装体系的设计、构建与研究

This team proposed a new concept for the controllable molecular assemby: catassembly, with its definition as: a catassembler is a substance (or a group of substances working synergistically) that increases the rate of an assembly process without modifying the overall standard Gibbs energy change; the process is called catassembly. This project uses a “backflush” manner to top-level design and organizes the team into three divisions: the small molecular catassembly, the macromolecular catassembly, and the simulation, theory and characterization of catassembly systems. We intend to develop various experimental systems to demonstrate the concept, disclose the laws and extend the meaning, and to investigate the thermodynamics and kinetics of the corresponding catassembly processes, in order to promote the characterization and theory study of molecular assembly. Our ultimate goal is to develop catassembly into a leading direction internationally.

项目组提出可控分子组装新思路—— “催组装”，并将其定义：催组剂是一类能够在不改变总吉布斯自由能变化的条件下加速组装的物质，这一被促进的过程可称为催组装。本项目通过“倒逼法”进行顶层设计并组织队伍，从小分子催组装、大分子催组装和催组装体系的模拟、理论与表征三方面入手，通过发展能够真正诠释上述定义的实验体系来验证概念、揭示规律、拓展内涵，并在此基础上研究相应催组装过程的热力学与动力学问题，从而推动组装表征方法和组装理论的研究，最终将催组装研究推向国际引领性方向。

项目组提出可控分子组装新思路—— “催组装”，并将其定义：催组剂是一类能够在不改变总吉布斯自由能变化的条件下加速组装的物质，这一被促进的过程可称为催组装。本项目通过“倒逼法”进行顶层设计并组织队伍，从小分子催组装、大分子催组装和催组装体系的模拟、理论与表征三方面入手，通过发展能够真正诠释上述定义的实验体系来验证概念、揭示规律、拓展内涵，并在此基础上研究相应催组装过程的热力学与动力学问题，从而推动组装表征方法和组装理论的研究，将催组装研究推向国际引领性方向。